Hey, I don’t know if it will live or not. The highest piston speeds I’m aware of are in NASCAR and they go 500 miles. There are a few generalities that may be helpful.
A while back modest cost engine pressure wave modeling code that handled supercharging was available. It did a pretty good job of getting you in the ball park and is a lot cheaper than cut and try with your engine.
As to cams, keep in mind that the strong intake pressure will negate much overlap by flowing out the exhaust. Just a touch for scavenging is all you need. Also, with the dense air/fuel charge, you probable will need a good bit of blow down to avoid losing power during the exhaust event.
Actual timing and lift is a function of intake/exhaust flow. With supercharging the exhaust needs all the help it can get. All things equal, two EX valves would seem the better approach (not that you have the choice) since the supercharging can cure many of the intake problems. For the same reason a lot more exhaust cam and flow is the better course.